Precise Manipulation of the Site and Stoichiometry of Capsid Modification Enables Optimization of Functional Adeno-Associated Virus Conjugates.
Erickson SB, Pham Q, Cao X, Glicksman J, Kelemen RE, Shahraeini SS, Bodkin S, Kiyam Z, Chatterjee A
Bioconjug Chem. 2024 Jan 17;35(1):64-71. doi: 10.1021/acs.bioconjchem.3c00411. Epub 2023 Dec 16.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 240057 | pIDTsmart-RC2-WT | Express AAV2 WT capsid |
| 240058 | pIDTsmart-RC2-454TAG | Express AAV2 capsid with ncAA mutant at site 454 |
| 240059 | pIDTsmart-RC2-delVP1-VP1-454TAG | Express AAV2 capsid with ncAA mutant at site 454 of VP1 |
| 240060 | pIDTsmart-RC2-delVP2-VP2-454TAG | Express AAV2 capsid with ncAA mutant at site 454 of VP2 |
| 240061 | pIDTsmart-RC2-delVP12-VP12-454TAG | Express AAV2 capsid with ncAA mutant at site 454 of VP1 and VP2 |
| 240062 | pIDTsmart-RC2-KO-delVP1-VP1-454TAG | Express AAV2-KO (R585A,R588A) capsid with ncAA mutant at site 454 of VP1 |
| 240063 | pIDTsmart-RC2-KO-454TAG | Express AAV2-KO (R585,588A) capsid with ncAA mutant at site 454 |