MFSD6 is an entry receptor for enterovirus D68.
Varanese L, Xu L, Peters CE, Pintilie G, Roberts DS, Raj S, Liu M, Ooi YS, Diep J, Qiao W, Richards CM, Callaway J, Bertozzi CR, Jabs S, de Vries E, van Kuppeveld FJM, Nagamine CM, Chiu W, Carette JE
Nature. 2025 Mar 25. doi: 10.1038/s41586-025-08908-0.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 239947 | pFUSE-rIgG-Fc2-MFSD8(L9)-Zeo | Expression of MFSD8 loop 9 tagged with rabbit IgG Fc2 |
| 239948 | pFUSE-rIgG-Fc2-MFSD6(L3)-Zeo | Expression of MFSD6 loop 3 tagged with rabbit IgG Fc2 |
| 239949 | pLentiCRISPRv2-ICAM-5-Puro | CRISPR KO of human ICAM-5 |
| 239950 | pLentiCRISPRv2-MFSD6-Puro | CRISPR KO of human MFSD6 |
| 239951 | pX458-MFSD6 | Encodes gRNA for human MFSD6 |
| 239953 | pLenti-CMV-MFSD6-Puro | Lentiviral vector to generate MFSD6 stable expressing cell line under CMV promoter |
| 239954 | pLenti-CMV-MFSD8-Puro | Lentiviral vector to generate MFSD8 stable expressing cell line under CMV promoter |
| 239955 | pLenti-CMV-MFSD6-mNeon-Puro | Lentiviral vector to generate mNeon-tagged MFSD6 stable expressing cell line under CMV promoter |