A TBK1-independent primordial function of STING in lysosomal biogenesis.
Lv B, Dion WA, Yang H, Xun J, Kim DH, Zhu B, Tan JX
Mol Cell. 2024 Oct 17;84(20):3979-3996.e9. doi: 10.1016/j.molcel.2024.08.026. Epub 2024 Sep 19.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 262579 | Flag-TurboID-NES | Expresses TurboID with a nuclear export signal in mammalian cells. |
| 262580 | Flag-HsSTING350 | Expresses truncated HsSTING lacking the C-terminal TBK1/IRF3 activation motifs in mammalian cells. |
| 262581 | Flag-MmSTING350 | Expresses truncated MmSTING lacking the C-terminal TBK1/IRF3 activation motifs in mammalian cells. |
| 262582 | Myc-TFEB-GFP | Expresses TFEB-GFP in mammalian cells. |
| 262583 | V5-SopF | Expresses SopF in mammalian cells. Prevents the recruitment of ATG16L1 to lysosomes. |
| 262584 | V5-SopF Y224D | Expresses an enzymatically dead mutant of SopF in mammalian cells. |
| 262585 | V5-RavZ | Expresses RavZ in mammalian cells. Removes conjugated ATG8s from membranes. |
| 262586 | V5-RavZ C268A | Expresses an enzymatically dead mutant of RavZ in mammalian cells. |