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Long G4-rich enhancers target promoters via a G4 DNA-based mechanism.

DeMeis JD, Roberts JT, Delcher HA, Godang NL, Coley AB, Brown CL, Shaw MH, Naaz S, Dahal A, Alqudah SY, Nguyen KN, Nguyen AD, Paudel SS, Shell JE, Patil SS, Dang H, O'Neal WK, Knowles MR, Houserova D, Gillespie MN, Borchert GM
Nucleic Acids Res. 2025 Jan 11;53(2):gkae1180. doi: 10.1093/nar/gkae1180. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
205467pGL4.10 promEXOC3Luciferase reporter of promoter activity
205468TOPO-LG4_chr5:550kb antisenseEnhancer containing plasmid used for assessing enhancer::promoter interactions
226453TOPO-SV40For subcloning of SV40 promoter or for assays using M13 phage

Antibodies from Article