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Joshua Mendell Lab: Specific tRNAs promote mRNA decay by recruiting the CCR4-NOT complex to translating ribosomes.

Zhu X, Cruz VE, Zhang H, Erzberger JP, Mendell JT
Science. 2024 Nov 22;386(6724):eadq8587. doi: 10.1126/science.adq8587. Epub 2024 Nov 22. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
245724Lenti-CMV-CNOT3-Tev-3xFlagExpress CNOT3-Tev-3xFlag in mammalian cells
245725Lenti-CMV-CNOT3-R59S-Tev-3xFlagExpress CNOT3-R59S-Tev-3xFlag in mammalian cells
245726Lenti-CMV-CNOT3-E95A-Tev-3xFlagExpress CNOT3-E95A-Tev-3xFlag in mammalian cells
245727Lenti-CMV-CNOT3-K105S-Tev-3xFlagExpress CNOT3-K105S-Tev-3xFlag in mammalian cells
245730lenti-CMV-TEV-3XFlagExpress Tev-3xFlag in mammalian cells

Antibodies from Article