Profound synthetic lethality between SMARCAL1 and FANCM.
Feng S, Liu K, Shang J, Hoeg L, Pastore G, Yang W, Roy S, Sastre-Moreno G, Young JTF, Wu W, Xu D, Durocher D
Mol Cell. 2024 Dec 5;84(23):4522-4537.e7. doi: 10.1016/j.molcel.2024.10.016. Epub 2024 Nov 6.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 246935 | pHIVT9-NAT-3xFlag-SMARCAL1 | Lentiviral vector that expresses wildtype Flag-tagged SMARCAL1 |
| 246936 | pHIVT9-NAT-3xFlag-SMARCAL1-ΔN | Lentiviral vector that expresses Flag-tagged SMARCAL1 with a deletion of the RPA-binding domain located in the N-terminal region (ΔN) |
| 246937 | pHIVT9-NAT-3xFlag-SMARCAL1-R764Q | Lentiviral vector that expresses Flag-tagged SMARCAL1 with a mutation in the ATP translocase domain (R764Q) |