Allosteric regulation of the Golgi-localized PPM1H phosphatase by Rab GTPases modulates LRRK2 substrate dephosphorylation in Parkinson's disease.

Adhikari A, Tripathi A, Chiang CY, Sherpa P, Pfeffer SR
J Biol Chem. 2025 Sep 3:110679. doi: 10.1016/j.jbc.2025.110679. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID	Plasmid	Purpose
240064	pET15b His SUMO mNeon L66R PPM1H	Expresses His SUMO mNeon (inserted in loop 1) L66R PPM1H phosphtase in bacterial cells
240065	pET15b His SUMO mNeon Δ37 PPM1H	Expresses His SUMO mNeon (inserted in loop1) Δ37 PPM1H in bacterial cells