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A novel approach towards a histone replacement system in Tetrapods

Pfisterer M, Pritz A, Parry A, Schmitz ML
PLoS One 21(2): e0342014 (2026) (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
240416pHREP-KD-1Sleeping Beauty vector for inducible expression of an shRNA using a shortened mir30 sequence. Allows co-selection with Puromycin.
240417pHREP-KD-1-shH2BSleeping Beauty vector for inducible expression of a chicken H2B targeting shRNA using a shortened mir30 sequence. Allows co-selection with Puromycin.
240419pHREP-RE-1-H2BSleeping Beauty vector for the expression of a polycistronic mRNA with shRNA resistant chicken H2B and Blasticidin resistance
240431pHREP-KD-2-shH4Sleeping Beauty vector for inducible expression of a chicken H4 targeting shRNA using a shortened mir30 sequence. Allows co-selection with Puromycin.
240432pHREP-LPEmpty landing pad vector with two Bxb1 recombination sites for RMCE and LNGFR + EGFP-HygroR for sorting/selection.
240433pHREP-LP-1xH2BLanding pad vector with two Bxb1 recombination sites for RMCE and LNGFR + EGFP-HygroR for sorting/selection and 1x inducible expression cassette for shRNA resistant chicken H2B.
240438pHREP-LP-2xH2BLanding pad vector with two Bxb1 recombination sites for RMCE and LNGFR + EGFP-HygroR for sorting/selection and 2x inducible expression cassette for shRNA resistant chicken H2B.
240439pHREP-LP-3xH2BLanding pad vector with two Bxb1 recombination sites for RMCE and LNGFR + EGFP-HygroR for sorting/selection and 3x inducible expression cassette for shRNA resistant chicken H2B.
240440pHREP-LP-4xH2BLanding pad vector with two Bxb1 recombination sites for RMCE and LNGFR + EGFP-HygroR for sorting/selection and 4x inducible expression cassette for shRNA resistant chicken H2B.
240441pHREP-KD-2Sleeping Beauty vector for inducible expression of an shRNA using a shortened mir30 sequence. Allows co-selection with Puromycin.
240580pHREP-KD-2-shCtrlSleeping Beauty vector for inducible expression of a unspecific control shRNA using a shortened mir30 sequence. Allows co-selection with Puromycin.
241994pHREP-KD-2-shH1Sleeping Beauty vector for inducible expression of a chicken H1 targeting shRNA using a shortened mir30 sequence. Allows co-selection with Puromycin.
241995pHREP-KD-2-shH3Sleeping Beauty vector for inducible expression of a chicken H3 targeting shRNA using a shortened mir30 sequence. Allows co-selection with Puromycin.
241996pHREP-KD-2-shH2BSleeping Beauty vector for inducible expression of a chicken H2B targeting shRNA using a shortened mir30 sequence. Allows co-selection with Puromycin.
241997pHREP-KD-2-shH2ASleeping Beauty vector for inducible expression of a chicken H2A targeting shRNA using a shortened mir30 sequence. Allows co-selection with Puromycin.

Antibodies from Article