A predatory gene drive for targeted control of self-transmissible plasmids.
Tsoi R, Son HI, Hamrick GS, Tang K, Bethke JH, Lu J, Maddamsetti R, You L
Sci Adv. 2025 Apr 4;11(14):eads4735. doi: 10.1126/sciadv.ads4735. Epub 2025 Apr 2.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 244463 | DoS1 | Containing RP4 oriT and inc sequence, for eliminating RP4 plasmid. |
| 244465 | DoS1ΔoriT | DoS1 derived plasmid without RP4 oriT |
| 244466 | DoS1ΔincΔoriT | DoS1 derived plasmid without RP4 oriT and inc |
| 244468 | DoS2-pOX38 | Targeting pOX38 plasmid |
| 244470 | DoS2-pCU1 | Targeting pCU1 plasmid |
| 244471 | DoS3 plasmid | Containing RP4 oriT and Cas9 module, for eliminating RP4 plasmid. |