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Development of Modular Geminivirus-Based Vectors for High Cargo Expression and Gene Targeting in Plants.

Neubauer M, Vollen K, Zhao C, Ascencio-Ibanez JT, Hanley-Bowdoin L, Stepanova AN, Alonso JM
Plant Biotechnol J. 2025 Sep 21. doi: 10.1111/pbi.70320. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
240715BCTVΔREP-pUPD2BCTV complementary sense ORFs with mutated Rep with GoldenBraid C1 grammar
240716BCTV-VS WT-pUPD2WT BCTV virion sense ORFs prior to domestication for GoldenGate cloning with A1-B1 Goldenbraid grammar
240717BCTVΔIR-pUPD2BCTV complementary sense ORFs lacking the IR. Has C1 Goldenbraid grammar.
240718BCTVΔVS-pUPD2BCTV IR lacking virion sense ORFs.
240719RT B2-B6-pUPD2GUS:NPTII repair template used for HDR experiments with compatible reporter lines. Has B2-B6 Goldenbraid grammar.
240720RT B6-pUPD2GUS:NPTII repair template used for HDR experiments with compatible reporter lines. Has B6 Goldenbraid grammar.
240721ZFN-pUPD2ZFN that targets the broken GUS:NPTII reporter with B2-B5 Goldenbraid grammar.
240722BCTV-YPET-pDGB3alpha2BCTV vector for YPET expression.
240723BCTVΔVS-YPET-pDGB3alpha1BCTV vector for YPET expression. Lacks the BCTV virion sense ORFs.
240724BCTV-RT-pDGB3alpha2BCTV vector containing the GUS:NPTII repair template for HDR experiments.
240725BCTVΔREP-YPET-pDGB3alpha1BCTV vector for YPET expression. Rep has been mutated.
240726BCTVΔVSΔREP-YPET-pDGB3alpha1BCTV vector for YPET expression. Lacks the BCTV virion sense ORFs and Rep has been mutated.
240727BCTVΔVSΔREP-RT-pDGB3alpha1BCTV vector containing the GUS:NPTII repair template for HDR experiments. Lacks the BCTV virion sense ORFs and Rep has been mutated.
240728BCTVΔREP-RT-pDGB3alpha1BCTV vector containing the GUS:NPTII repair template for HDR experiments. Rep has been mutated.
24072935S-ZFN-pDGB3alpha1Encodes a ZFN that targets the broken GUS:NPTII reporter.
240746BCTV-CS-pUPD2 BCTV complementary sense ORFs with C1 Goldenbraid grammar
240747BeYDV-RT-pUPD2 BeYDV viral vector containing a repair template.
240748BCTV-VS domesticated-pUPD2Domesticated BCTV virion sense ORFs with A1-B1 Goldenbraid grammar

Antibodies from Article