The internal limiting basement membrane inhibits functional engraftment of transplanted human retinal ganglion cells in vivo.
Aguzzi EA, Mary S, Vardanjani MM, Godinez DR, Kimball E, Bonakdar B, Zhang KY, Du J, Nagalingam A, Yutzy W, Quillen S, Hariharakumar S, Quigley HA, Zack DJ, Handa JT, Johnson TV
Sci Transl Med. 2026 Apr 29;18(847):eadr1062. doi: 10.1126/scitranslmed.adr1062. Epub 2026 Apr 29.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 241022 | pAAV-CAG2-GCaMP6s | An AAV transfer plasmid expressing the GCaMP6s genetically encoded calcium indicator under control of the ubiquitously expressed CAG2 promoter. |
| 241023 | AAVS1-CAG-GCaMP6s | An HDR plasmid for the AAVS1 safe harbor locus carrying a gene cassette consisting of GCaMP6s under control of a CAG promoter and a WPRE. |