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An orthogonalized PYR1-based CID module with reprogrammable ligand-binding specificity.

Park SY, Qiu J, Wei S, Peterson FC, Beltran J, Medina-Cucurella AV, Vaidya AS, Xing Z, Volkman BF, Nusinow DA, Whitehead TA, Wheeldon I, Cutler SR
Nat Chem Biol. 2024 Jan;20(1):103-110. doi: 10.1038/s41589-023-01447-7. Epub 2023 Oct 23. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
241277pACT-HAB1_starOrthogonal PYR1/HAB1 sensor module

Antibodies from Article