Richard Possemato Lab: Targeting DNA polymerase epsilon leads to tumor clearance and activation of an NF-_B-mediated inflammatory response in triple negative breast cancer

Unpublished

Plasmids from Article

ID	Plasmid	Purpose
241437	pCW57.1 DOX off blast POLE	Expresses DOX-suppressible POLE
241438	pCW57.1 DOX off blast POLD1	Expresses DOX-suppressible POLD1
241439	pCW57.1 DOX off puro IKBKG	Expresses DOX-suppressible IKBKG
241440	pCW57.1 DOX off puro RELA	Expresses DOX-suppressible RELA
241441	pLENTICRISPR V2 sgPOLE	Delete POLE
241442	pLENTICRISPR V2 hygro sgmPOLE_1	Delete mouse Pole
241443	pLENTICRISPR V2 hygro sgmPOLE_2	Delete mouse Pole
241444	pLENTICRISPR V2 sgPOLD	Delete POLD1
241445	pLENTICRISPR V2 Hygro sgRELA_1	Delete RELA
241446	pLENTICRISPR V2 Hygro sgRELA_4	Delete RELA
241447	pLENTICRISPR V2-mCherry sgmRELA_1	Delete mouse Rela
241448	pLENTICRISPR V2 Hygro sgRELB_2	Delete RELB
241449	pLENTICRISPR V2 Hygro sgIKBKG_1	Delete IKBKG
241450	pLENTICRISPR V2 Hygro sgIKBKG_2	Delete IKBKG
241451	pLENTICRISPR V2 Hygro sgDDX58	Delete DDX58 (RIG-I)
241452	pLENTICRISPR V2 Hygro sgRELB_1	Delete RELB
241453	pLENTICRISPR V2-mCherry sgmRELA_2	Delete mouse Rela
241454	pLENTICRISPR V2 sgCGAS_1	Delete CGAS
241455	pLENTICRISPR V2 sgCGAS_2	Delete CGAS
241456	pLENTICRISPR V2 sgTMEM173_1	Delete TMEM173 (STING)
241457	pLENTICRISPR V2 sgTMEM173_2	Delete TMEM173 (STING)