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A base editing platform for the correction of cancer driver mutations unmasks conserved p53 transcription programs.

Wang P, Sen R, Buchholz F, Sayed S
Genome Biol. 2025 Jul 22;26(1):217. doi: 10.1186/s13059-025-03667-7. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
242000Lenti NG-ABE8e_P2A_GFP + PuroRLentiviral plasmid for generation of cell lines stably expressing NG-ABE8e base editor. NG-ABE8e expression can be followed by GFP fluorescence. Contains PGK-puromycin resistance cassette.

Antibodies from Article