An ultraconserved snoRNA-like element in long noncoding RNA CRNDE promotes ribosome biogenesis and cell proliferation.
Lee JS, Dan T, Zhang H, Cheng Y, Rehfeld F, Brugarolas J, Mendell JT
Mol Cell. 2025 Apr 17;85(8):1543-1560.e10. doi: 10.1016/j.molcel.2025.03.006. Epub 2025 Apr 3.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 242177 | XLone-Unspliced CRNDE | Express doxycycline inducible Unspliced CRNDE in mammalian cells |
| 242178 | XLone-Fully-spliced CRNDE | Express doxycycline inducible Fully-spliced CRNDE in mammalian cells |
| 242179 | XLone-CRNDEUCE (5 kb) | Express doxycycline inducible 5 kb UCE-containing CRNDE in mammalian cells |
| 242180 | XLone-UCE intron | Express doxycycline inducible UCE-containing intron of CRNDE in mammalian cells |
| 242181 | XLone-UCE intron 5' deletion | Express doxycycline inducible UCE intron 5' deletion of CRNDE in mammalian cells |
| 242182 | XLone-UCE intron 3' deletion | Express doxycycline inducible UCE intron 3' deletion of CRNDE in mammalian cells |
| 242183 | XLone-UCE intron upstream | Express doxycycline inducible intron fragment upstream of UCE of CRNDE in mammalian cells |
| 242184 | XLone-UCE | Express doxycycline inducible UCE intron of CRNDE in mammalian cells |
| 242185 | XLone-UCE mutant | Express doxycycline inducible UCE 32S binding mutation of CRNDE in mammalian cells |
| 242186 | XLone-UCE intron (DF3-2) | Express doxycycline inducible CRNDE UCE intron with deletion of the eIF6 binding site F3-2 in mammalian cells |
| 242187 | hAAVS-RPL23a-SNAP | Express RPL23a-SNAP in mammalian cells |
| 242188 | pLenti-eIF6-3XFlag | Express eIF6-3xFlag in mammalian cells |