TNO155 is a selective SHP2 inhibitor to target PTPN11-dependent oral squamous cell carcinoma.
Chai AWY, Tan YH, Ooi S, Yee PS, Yee SM, Cheong SC
Heliyon. 2024 Oct 22;10(21):e39677. doi: 10.1016/j.heliyon.2024.e39677. eCollection 2024 Nov 15.
(Link opens in a new window)
PubMed
(Link opens in a new window)
Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 208427 | pKLV2-U6gRNA5(hPTPN11_1k)-PGKpuro2ABFP-W | Lentiviral gRNA plasmid targeting human PTPN11 gene, co-expression of BFP tag |
| 208428 | pKLV2-U6gRNA5(hPTPN11_2b)-PGKpuro2ABFP-W | Lentiviral gRNA plasmid targeting human PTPN11 gene, co-expression of BFP tag |
| 208429 | pKLV2-U6gRNA5(hMTOR_1k)-PGKpuro2ABFP-W | Lentiviral gRNA plasmid targeting human MTOR gene, co-expression of BFP tag |
| 208430 | pKLV2-U6gRNA5(hMTOR_2b)-PGKpuro2ABFP-W | Lentiviral gRNA plasmid targeting human MTOR gene, co-expression of BFP tag |
| 208431 | pKLV2-U6gRNA5(hEGFR_1k)-PGKpuro2ABFP-W | Lentiviral gRNA plasmid targeting human EGFR gene, co-expression of BFP tag |
| 208432 | pKLV2-U6gRNA5(hEGFR_2b)-PGKpuro2ABFP-W | Lentiviral gRNA plasmid targeting human EGFR gene, co-expression of BFP tag |