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beta-catenin functions as a molecular adapter for disordered cBAF interactions.

Chan YS, Gao Q, Robinson SA, Wang W, Filandrova R, Weinhold LM, Cabrera ML, Zhang M, Ambati CSR, Lerario AM, Putluri N, Kiseljak-Vassiliades K, Wierman ME, Habra MA, Hammer GD, Veverka V, Cermakova K, Hodges HC
Mol Cell. 2025 Jul 15:S1097-2765(25)00576-3. doi: 10.1016/j.molcel.2025.06.026. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
242216pMAL-c4X-MBP-ARID1A-IDR2Expression of MBP-tagged human ARID1A IDR2 (a.a. 1170-1610) in E. coli
242218pPB-CAG-CTNNB1-deltaN-HAExpression of human β-catenin ∆N terminal IDR (deletion of a.a. 2-133) using piggyBac transposition
242221pPB-CAG-CTNNB1-delta7-9-HAExpression of human β-catenin ∆arm 7-9 (deletion of a.a. 395-520) using piggyBac transposition
242225pGEX-5X-1-GST-ArmadilloExpression of GST-tagged human β-catenin Armadillo repeats without IDRs (deletion of a.a. 2-133 and 672-781) in E. coli
242226pGEX-5X-1-GST-Armadillo-delta4-6Expression of GST-tagged human β-catenin Armadillo repeats ∆4-6 without IDRs (deletion of a.a. 2-133, 268-394, and 672-781) in E. coli

Antibodies from Article