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The function of MYC in base excision repair protects against RAS-induced senescence.

Faraco CCF, Zhu W, Fortier AM, Ramdzan ZM, Vickridge E, Ong V, Goudreau F, Djerir B, Bellemare J, Gu S, Zhang H, Carroll BL, Krishnan SS, Leduy L, Guarne A, Park M, Marechal A, Nepveu A
Nucleic Acids Res. 2025 Jul 19;53(14):gkaf706. doi: 10.1093/nar/gkaf706. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
242618M20Strep-MYC deltaCTD-His protein expression in bacteria
242619M24Strep- MYC deltaCTD, deltaMB0-1-His protein expression in bacteria
242620M51Strep-MYC-His protein expression in bacteria
242621M53Strep-Flag-MYCMutMBII-His protein expression in bacteria
242622M54Strep-Flag-MYCMutMBIIIa-His protein expression in bacteria
242623M55Strep-Flag-MYCMutMBIV-His protein expression in bacteria
242624M101Strep-MYC-MutBoxIIIb-His protein expression in bacteria
242625M56BDox-inducible MYC knockdown
242626M74MYC knockdown
242627M76MYC knockdown + rescue
242628M76BMYCMutMBIV expression
242629M77MYC knockdown + rescue
242630M77BMYCMutMBIIIa expression
242631M79MYC knockdown
242632M80MYC knockdown
242633M87MYC expression
242634M88MYCdeltaCTD expression
242635M91lower MYCdeltaCTD expression
242636M92lower MYC expression
242637M93MYC knockdown + rescue
242638M99MYC knockdown + rescue
242639pBabe-Hygro-RASRAS expression

Antibodies from Article