Skip to main content

Alpha-ketoglutarate mitigates insulin resistance and metabolic inflexibility in a mouse model of Ataxia-Telangiectasia.

Sun JK, Hart RP, Herrup K, Peng AZ, Wong GC, Wu D, Kwan KM, Chow KH
Nat Commun. 2025 Oct 21;16(1):9312. doi: 10.1038/s41467-025-64360-8. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
242809FUGW-EGFP-mHif1aLentiviral vector expressing mouse Hif1a tagged with an N-terminal EGFP
242811FUGW-EGFP-mHif1a-T163ELentiviral vector expressing mouse Hif1a-T163E mutant tagged with an N-terminal EGFP
242812FUGW-EGFP-mPkm2Lentiviral vector expressing mouse Pkm2 tagged with an N-terminal EGFP
242813FUGW-EGFP-mPkm2-T328ALentiviral vector expressing mouse Pkm2-T328A mutant tagged with an N-terminal EGFP
242814FUGW-EGFP-mPkm2-T328ELentiviral vector expressing mouse Pkm2-T328E mutant tagged with an N-terminal EGFP

Antibodies from Article