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ABE9 fused to SpRY Cas9 nickase enables precise generation of bystander free mouse models

Ong JK, Bhunia S, Hilbert B, Kirschner V, Duglosz S, Zimmermann F, Freichel M, Cornean A
Sci Rep (2026). https://doi.org/10.1038/s41598-026-40642-z (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
242976ABE9-SpRYA-to-G base editor fused to PAM-flexible SpRY-Cas9 nickase.
242977pEF1a_ABE9-SpRYA-to-G base editor fused to PAM-flexible SpRY-Cas9 nickase.

Antibodies from Article