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TFEB overexpression alleviates autophagy-lysosomal deficits caused by progranulin insufficiency.

Nader WO, Brown KS, Boyle NR, Kaplelach AK, Abdelaziz SM, Davis SE, Aljabi Q, Hakim AR, Davidson AG, Vollmer GA, Wright LC, Echols JB, Saad J, Pena NS, Arrant AE
Sci Rep. 2025 Jul 19;15(1):26217. doi: 10.1038/s41598-025-12268-0. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
243758AAV-CAG-HA-mTFEBAAV plasmid expressing HA-tagged codon-optimized mouse TFEB under the CAG promoter.

Antibodies from Article