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LINE1 elements at distal junctions of rDNA repeats regulate nucleolar organization in human embryonic stem cells.

Ataei L, Zhang J, Monis S, Giemza K, Mittal K, Yang J, Shimomura M, McStay B, Wilson MD, Ramalho-Santos M
Genes Dev. 2025 Feb 3;39(3-4):280-298. doi: 10.1101/gad.351979.124. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
247542DJ-L1 gRNA #1CRISPRi-KD of human DJ LINE1
247543DJ-L1 gRNA #3CRISPRi-KD of human DJ LINE1
247544DJ-L1 gRNA #4CRISPRi-KD of human DJ LINE1
247545DJ-L1 gRNA #5CRISPRi-KD of human DJ LINE1
247546InterIR gRNA #2negative control for Crispri KD
247547IR InterIR gRNA #5negative control for Crispri KD
247548rDNA-adj gRNA #1negative control for Crispri KD
247549rDNA-adj gRNA #3negative control for Crispri KD

Antibodies from Article