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An updated inventory of genes essential for oxidative phosphorylation identifies a mitochondrial origin in familial Meniere's disease.

Harhai M, Foged MM, Zarges C, Landoni JC, Chollet S, Simonelli M, Recazens E, Lisci M, Laban N, Manley S, Riemer J, Lopez-Escamez JA, Lysakowski A, Jourdain AA
Cell Rep. 2025 Jul 25;44(8):116069. doi: 10.1016/j.celrep.2025.116069. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
244847pLentiCRISPR ATP23 sg1Knockout of human ATP23
244848pLentiCRISPR ATP23 sg2Knockout of human ATP23
244849pLentiCRISPR IMMP1L sg1Knockout of human IMMP1L
244850pLentiCRISPR IMMP1L sg2Knockout of human IMMP1L
244851pLentiCRISPR IMMP2L sg1Knockout of human IMMP2L
244852pLentiCRISPR IMMP2L sg2Knockout of human IMMP2L
244853pLentiCRISPR PARL sg1Knockout of human PARL
244854pLentiCRISPR PARL sg2Knockout of human PARL
244855pLentiCRISPR V2 ALAD_sg1Knockout of human ALAD
244856pLentiCRISPR V2 ALAD_sg2Knockout of human ALAD
244857pLentiCRISPR V2 CLUH sg1Knockout of human CLUH
244858pLentiCRISPR V2 CLUH sg2Knockout of human CLUH
244859pLentiCRISPR V2 HMBS_sg1Knockout of human HMBS
244860pLentiCRISPR V2 HMBS_sg2Knockout of human HMBS
244861pLentiCRISPR V2 PAPOLA_sg1Knockout of human PAPOLA
244862pLentiCRISPR V2 PAPOLA_sg2Knockout of human PAPOLA
244863pLentiCRISPR V2 puro HTRA2 sg1 Knockout of human HTRA2
244864pLentiCRISPR V2 puro HTRA2 sg2 Knockout of human HTRA2
244865pLentiCRISPR V2 sgOMA1 sg1Knockout of human OMA1
244866pLentiCRISPR V2 sgOMA1 sg2Knockout of human OMA1
244867pLentiCRISPR V2 sgYME1L1 sg1Knockout of human YME1L1
244868pLentiCRISPR V2 sgYME1L1 sg2Knockout of human YME1L1
244869pLentiCRISPR V2 SLC31A1_sg1Knockout of human SLC31A1
244870pLentiCRISPR V2 SLC31A1_sg2Knockout of human SLC31A1
244871pLentiCRISPR V2 SQLE_sg1Knockout of human SQLE
244872pLentiCRISPR V2 SQLE_sg2Knockout of human SQLE
244873pLentiCRISPR V2 UROS_sg1Knockout of human UROS
244874pLentiCRISPR V2 UROS_sg2Knockout of human UROS
244875pLentiCRISPR_blast_FAM136A_sg1Knockout of human FAM136A
244876pLentiCRISPR_blast_FAM136A_sg2Knockout of human FAM136A
244877pLentiCRISPR_puro_FAM136A_sg1Knockout of human FAM136A
244878pLentiCRISPR_puro_FAM136A_sg2Knockout of human FAM136A
244879pLV-FAM136A-mutant-3xFLAG-hygroOverexpression of mutant human FAM136A
244880pLV-FAM136A-WT-3xFLAG-hygroOverexpression of wild-type human FAM136A
244881pTwist Amp High Copy ENDOG-HAIn vitro transcription of human ENDOG downstream of SP6 promoter
244882pTwist Amp High Copy FAM136A-HA mutantIn vitro transcription of mutant human FAM136A downstream of SP6 promoter
244883pTwist Amp High Copy FAM136A-HA WTIn vitro transcription of wild-type FAM136A downstream of SP6 promoter

Antibodies from Article