AAVs targeting human carbonic anhydrase IV enhance gene delivery to the brain.
Lin C, Chen X, Hoang JD, Ristic F, Fan Y, Jang S, Chung JHA, Sullivan EE, Gawda T, Kavvathas B, Tran I, Li Y, Steele AD, Shay TF, Gradinaru V
Cell Rep. 2025 Oct 31;44(11):116419. doi: 10.1016/j.celrep.2025.116419.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 244906 | pUCmini-iCAP-hCA4-IV77 | Rep/Cap plasmid for producing variant AAV-hCA4-IV77 |
| 244907 | pUCmini-iCAP-hCA4-IV68 | Rep/Cap plasmid for producing variant AAV-hCA4-IV68 |
| 244908 | pAAV-CAG-hCA4-miR122 | AAV transgene plasmid encoding human CA4 with miR-122 target site |
| 244909 | pAAV-CAG-TdTomato-miR122 | AAV transgene plasmid encoding TdTomato with miR-122 target site |