Tau accumulation in astrocytes of the dentate gyrus induces neuronal dysfunction and memory deficits in Alzheimer's disease.
Richetin K, Steullet P, Pachoud M, Perbet R, Parietti E, Maheswaran M, Eddarkaoui S, Begard S, Pythoud C, Rey M, Caillierez R, Q Do K, Halliez S, Bezzi P, Buee L, Leuba G, Colin M, Toni N, Deglon N
Nat Neurosci. 2020 Dec;23(12):1567-1579. doi: 10.1038/s41593-020-00728-x. Epub 2020 Nov 9.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
245075 | SIN-cPPT-G1B3-mitoGO-ATeam2-WPRE-miR124T | Mitochondrial ATP biosensor, with miRNA-124 target sequence to repress transgene expression in neurons |