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A PDZ-RapGEF promotes synaptic development in C. elegans through a Rap/Rac signaling pathway.

Lamb R, Scales M, Watkins J, Werner M, Cherra SJ
Development. 2025 Aug 1:dev.204678. doi: 10.1242/dev.204678. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
245763pBD22Allows for mCherry entry into Gateway Vectors
245764pBD24Allows for rap-1::mCherry entry into Gateway Vectors
245765pBD25Allows for rap-1::mGFP entry into Gateway Vectors
245766pBD28Allows for tiam-1::mGFP entry into Gateway Vectors
245767pBD30Expresses rap-1::mCherry in cholinergic motor neurons
245768pBD31Expresses rap-1::mGFP in cholinergic motor neurons
245769pBD34Expresses tiam-1::mGFP in cholinergic motor neurons
245770pREA12Allows for mCherry::RBD::T2A::rac-2::mGFP entry into Gateway Vectors
245771pREA16Expresses mCherry::RBD::T2A::rac-2::mGFP in cholinergic motor neurons
245772pSJC316Allows for rap-1(G12V)::mGFP entry into Gateway Vectors
245773pSJC317Allows for rac-2::mGFP entry into Gateway Vectors
245774pSJC318Allows for rac-2(G12V)::mGFP entry into Gateway Vectors
245775pSJC319Expresses rap-1(G12V)::mGFP in cholinergic motor neurons
245776pSJC320Expresses rac-2::mGFP in cholinergic motor neurons
245777pSJC321Expresses rac-2(G12V)::mGFP in cholinergic motor neurons

Antibodies from Article