C. elegans Cytoplasmic Isocitrate Dehydrogenase Neomorphic G98N and R133H Mutants Produce the Oncometabolite 2-Hydroxyglutarate.
Bouchard M, McAllister A, Bourlett NS, Hoyt C, Calcul L, Walstrom KM
Int J Mol Sci. 2025 Aug 25;26(17):8238. doi: 10.3390/ijms26178238.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 224142 | IDH1_WT | IPTG-inducible expression of C. elegans protein IDH-1 with a chitin tag |
| 224143 | IDH1_G98N | IPTG-inducible expression of C. elegans protein IDH-1(G98N) with a chitin tag |
| 224144 | IDH1_R133H | IPTG-inducible expression of C. elegans protein IDH-1(R133H) with a chitin tag |