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Knocking out ARL13B completely abolishes primary ciliogenesis in cell lines.

Mahajan D, Chia HM, Lu L
Sci Rep. 2025 Jul 24;15(1):26980. doi: 10.1038/s41598-025-11124-5. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
246838ARL13B-(T35N)-GFPExpress Arl13B (resistance to sgRNA), tagged with GFP, with T35N mutation
246839ARL13B-(R79Q)-GFPExpress Arl13B (resistance to sgRNA), tagged with GFP, with R79Q mutation
246841ARL13B-(R200C)-GFPExpress Arl13B (resistance to sgRNA), tagged with GFP, with R200C mutation
246842ARL13B-(C8C9- SS)-GFPExpress Arl13B (resistance to sgRNA), tagged with GFP, with C8C9-SS mutation
246843ARL13B-(ΔGTPase)- GFPExpress Arl13B (resistance to sgRNA) with deletion of GTPase, tagged with GFP
246845ARL13B-(ΔIDR)-GFPExpress Arl13B (resistance to sgRNA) with deletion of Intrinsically Disordered Region, tagged with GFP
246847ARL13B-GFP(1-245)Express Arl13B (resistance to sgRNA), aa1-245, tagged with GFP

Antibodies from Article