Binding of MBD proteins to DNA blocks Tet1 function thereby modulating transcriptional noise.
Ludwig AK, Zhang P, Hastert FD, Meyer S, Rausch C, Herce HD, Muller U, Lehmkuhl A, Hellmann I, Trummer C, Storm C, Leonhardt H, Cardoso MC
Nucleic Acids Res. 2017 Mar 17;45(5):2438-2457. doi: 10.1093/nar/gkw1197.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 246922 | pCAG-mcherry-Tet1CD (pc2547) | Expresses mCherry-tagged catalytic active domain of mouse Tet1 in mammalian cells. N-terminal tagged to mCherry. |
| 246923 | pCAG-mcherry-Tet1CDmut (pc2815) | Expresses mCherry-tagged mutated catalytic active domain of mouse Tet1 in mammalian cells. N-terminal tagged to mCherry. |
| 246924 | pFBDMeGmTet1CD (pc2838) | Expresses mCherry-tagged catalytic active domain of mouse Tet1 in mammalian cells. N-terminal tagged to GFP. |
| 246925 | pFBDMchmTet1CD (pc2859) | Expresses mCherry-tagged catalytic active domain of mouse Tet1 in mammalian cells. N-terminal tagged to mCherry. |