Functional RNA splitting drove the evolutionary emergence of type V CRISPR-Cas systems from transposons.
Jin S, Zhu Z, Li Y, Zhang S, Liu Y, Li D, Li Y, Luo Y, Cheng Z, Zhao KT, Gao Q, Yang G, Li H, Liang R, Zhang R, Qiu JL, Zhang YE, Liu JG, Gao C
Cell. 2025 Sep 29:S0092-8674(25)01035-9. doi: 10.1016/j.cell.2025.09.004.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 246928 | pEffector-LaTranC-CRISPR RNA | for E.coli plasmid interference and PAM depletion assays |
| 246931 | pCMV-LaTranC | for HEK293T human cell genome editing |