An iterative deep learning-guided algorithm for directed protein evolution.
Li X, Wang Q, Li J, Tang F, Yang X, Lin Z
iScience. 2025 Aug 7;28(9):113324. doi: 10.1016/j.isci.2025.113324. eCollection 2025 Sep 19.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 249257 | pACYC-PJ23100-dpGFP | An avGFP mutant designed by DeepDE that achieved a remarkable 74.3-fold increase in activity over four rounds of evolution, far surpassing the benchmark superfolder GFP. |