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Stuffed Epimerase Domains of Pyochelin Biosynthesis are Defunct Methyltransferases.

Ronnebaum TA, Meneely KM, Horsman GP, Prisinzano TE, Lamb AL
Biochemistry. 2025 Sep 16;64(18):3919-3934. doi: 10.1021/acs.biochem.5c00172. Epub 2025 Aug 26. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
242092PpPchENonribosomal peptide synthetase from Pseudomonas protegens for the production of enantiopyochelin
242093SvPchENonribosomal peptide synthetase from Streptomyces venezuluelae for the production of watasemysin
242094BsSFP4'phosphopantetheinyl transferase from Bacillus subtilis
242095BsSrfDThioesterase from Bacillus subtilis
242103PaPchE-AEAdenylase-epimerase didomain of the nonribosomal peptide synthetase PchE from Pseudomonas aeruginosa for the production of pyochelin

Antibodies from Article