rAAV2/7 vector-mediated overexpression of alpha-synuclein in mouse substantia nigra induces protein aggregation and progressive dose-dependent neurodegeneration.
Oliveras-Salva M, Van der Perren A, Casadei N, Stroobants S, Nuber S, D'Hooge R, Van den Haute C, Baekelandt V
Mol Neurodegener. 2013 Nov 25;8:44. doi: 10.1186/1750-1326-8-44.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 247940 | pAAV-CMVenh synapsin-intron-aSYNUCLEIN WT | AAV transfer plasmid encoding the human α-SYN under the control of the CMVie enhanced synapsin1 promoter |
| 247941 | pAAV-CMVenh synapsin-intron-eGFP | AAV transfer plasmid encoding enhanced Green Fluoresence Protein control of the CMVie enhanced synapsin1 promoter |