Structures of the human LONP1 protease reveal regulatory steps involved in protease activation.
Shin M, Watson ER, Song AS, Mindrebo JT, Novick SJ, Griffin PR, Wiseman RL, Lander GC
Nat Commun. 2021 May 28;12(1):3239. doi: 10.1038/s41467-021-23495-0.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 247937 | pET20b-His6-LONP1 | Expression of human LONP1 with methionine 115 as its first residue (mature mitochondrial-matrix localized form) |
| 247938 | pET20b-His6-LONP1-Walker B mutant (E591A) | Expression of human LONP1 with methionine 115 as its first residue (mature mitochondrial-matrix localized form) and Walker B mutant (E591A) |
| 247939 | pET20b-His6-LONP1-Pore Loop 2 mutant (Y599A) | Expression of human LONP1 with methionine 115 as its first residue (mature mitochondrial-matrix localized form) Pore Loop 2 mutant (Y599A) |