Inhibition of RAS-driven signaling and tumorigenesis with a pan-RAS monobody targeting the Switch I/II pocket.
Wallon L, Khan I, Teng KW, Koide A, Zuberi M, Li J, Ketavarapu G, Traaseth NJ, O'Bryan JP, Koide S
Proc Natl Acad Sci U S A. 2022 Oct 25;119(43):e2204481119. doi: 10.1073/pnas.2204481119. Epub 2022 Oct 17.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 248049 | pHBT-HRAS174 | To express His6 tag-Avi tag-TEV cleavage site-HRAS (residues 1-174) in E. coli, under the T7 promoter. |
| 248050 | pHBT-KRAS174 | To express His6 tag-Avi tag-TEV cleavage site-KRAS (residues 1-174) in E. coli, under the T7 promoter. |
| 248051 | pHBT-NRAS174 | To express His6 tag-Avi tag-TEV cleavage site-NRAS (residues 1-174) in E. coli, under the T7 promoter. |