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A human-specific regulatory mechanism revealed in a pre-implantation model.

Fueyo R, Wang S, Crocker OJ, Swigut T, Nakauchi H, Wysocka J
Nature. 2025 Oct 1. doi: 10.1038/s41586-025-09571-1. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
248161pB-EF1a-CuO-KRAB-dCas9-BFP-CymR-PuroExpresses KRAB fused to dCas9 and BFP upon cumate induction
248162pB-Ef1a-HERVK-proteinsExpresses HERVK proteins and tagBFP

Antibodies from Article