SpeckSeq enables high-throughput functional stratification of MEFV variants in autoinflammatory diseases.
Bronnec P, Dalmon S, Briand C, Allatif O, Broly M, Marcotte M, Lombardi G, Barthes K, Martel N, Hughes S, Gillet B, Milhavet F, Atilgan A, Bachelez H, Palmeri S, Prigione I, Madrange M, Savey L, Moutschen M, Jeru I, El Moussaoui M, Belot A, Sbidian E, Carbone A, Jamilloux Y, Gattorno M, Smahi A, Georgin-Lavialle S, Boursier G, Magnotti F, Henry T
J Exp Med. 2026 Feb 2;223(2):e20251065. doi: 10.1084/jem.20251065. Epub 2025 Dec 3.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 248187 | SpeckSeq library | The SpeckSeq library is a pooled lentiviral plasmid library containing 229 distinct variants of the MEFV gene, each linked to a unique barcode. |