Discovery and protein language model-guided design of hyperactive transposases.
Ivancic D, Agudelo A, Lindstrom-Vautrin J, Jaraba-Wallace J, Gallo M, Das R, Ragel A, Herrero-Vicente J, Higueras I, Billeci F, Sanvicente-Garcia M, Petazzi P, Ferruz N, Sanchez-Mejias A, Guell M
Nat Biotechnol. 2025 Oct 2. doi: 10.1038/s41587-025-02816-4.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 248198 | pCMV_PB_Poetur | Poetur transposase expressing plasmid |
| 248199 | pCMV_PB_Antgra4 | Antgra4 transposase expressing plasmid |
| 248200 | excision_reporter_HyPB | HyPB and synthetic transposase excision reporter and targeted integration reporter |
| 248201 | pTIR_HyPB_RFP | HyPB RFP cargo plasmid |
| 248202 | pTIR_Poetur_RFP | Poetur RFP cargo plasmid |
| 248203 | pTIR_Antgra4_RFP | Antgra4 RFP cargo plasmid |