Comparative gene editing reduces dopamine receptor levels across rodent species.

Karkare SC, Aspesi D, Garner KM, Schut EHS, Albers HE, Meye FJ, Murugan M, Boender AJ
bioRxiv [Preprint]. 2025 Oct 21:2025.10.21.683401. doi: 10.1101/2025.10.21.683401. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID	Plasmid	Purpose
231400	pAAV-u6-gRNA(deltaD1)-hSyn-mCherry	Knockdown of DRD1 across rodent species
231401	pAAV-u6-gRNA(deltaD2)-hSyn-mCherry	Knockdown of DRD2 across rodent species
231405	pAAV-u6-gRNA(CTRL)-hSyn-mCherry	CTRL knockdown gRNA