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A Brain Reward Circuit Inhibited By Next-Generation Weight Loss Drugs.

Godschall EN, Gungul TB, Sajonia IR, Buyukaksakal AK, Li OD, Ogilvie S, Keeler AB, Tian G, Koita O, Shi Y, Deutsch TCJ, Crook M, Zhang Y, Conley NJ, Webster AN, Calhan OY, Liu W, Akkoub A, Malik K, West KI, Michel-Le S, Karthikeyan A, van Gerven G, Beier KT, Zweifel LS, Patel MK, Campbell JN, Deppmann CD, Guler AD
bioRxiv [Preprint]. 2025 Jun 14:2024.12.12.628169. doi: 10.1101/2024.12.12.628169. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
249034AG0053 LGA (DIO-hGLP1R)Expression of Wild Type Human GLP1R, Cre dependent, under hSyn promoter
249035AG0057 LGA (DIO-mGlp1r)Expression of Wild Type Mouse Glp1r, Cre dependent under hSyn promoter
249036AG0058 LGA (DIO-mGlp1r-S33W)Expression of Mutant Mouse Glp1r-S33W, Cre dependent under hSyn promoter

Antibodies from Article