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STT3A is essential for Wnt signaling and represents a target for cancers driven by RNF43 deficiency.

He Z, Chen S, Suo J, Xia K, Liu M, Ma J, Chu Y, Wang C, Xie Y, Jiang W, Du H, Chen S, Zhou Z, Li M, Wei Q, Zhao Y, Chen J, Li L, Zeng Y, Zou W, Lin M, Jiang H
Cell Chem Biol. 2025 Oct 22:S2451-9456(25)00306-X. doi: 10.1016/j.chembiol.2025.10.001. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
248843DDT WntDouble Death Trap (DDT) Wnt reporter Containing FKBP12(F36V)-ΔCaspase9 (FC) and Puromycin Resistance Gene for Assessing Wnt Signaling

Antibodies from Article