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A synthetic transcription cascade enables direct in planta shoot regeneration for transgenesis and gene editing in multiple plants.

Kshetry AO, Ghose K, Alok A, Devkar V, Raman V, Stupar RM, Herrera-Estrella L, Zhang F, Patil GB
Mol Plant. 2025 Nov 6:S1674-2052(25)00322-3. doi: 10.1016/j.molp.2025.09.017. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
249641WEipt1BeYDV replicon with WIND1, ESR1-ipt cascade, sgRNAs targeting N. benthamiana PDS. RUBY as reporter.
249642WEipt2BeYDV replicon with WIND1, ESR1-ipt cascade, Cas9 and gRNAs targeting soybean PDS, RUBY as a reporter
249649WINDrubyBeYDV replicon with WIND1 and RUBY cascade
249650WErubyBeYDV replicon with WIND1, ESR1-RUBY cascade
249675WEwusBeYDV replicon with WIND1, ESR1-ZmWUS cascade, sgRNA targeting N. benthamiana PDS. RUBY as reporter.
249677WEbbmBeYDV replicon with WIND1, ESR1-GmBBM cascade, sgRNA targeting N. benthamiana PDS. RUBY as reporter.
249678ESRrubyBeYDV replicon with ESR1-RUBY cascade.

Antibodies from Article