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Lysosomal down-regulation of the mu opioid receptor is opposed by the Retromer complex.

Dagunts A, Adoff H, Novy B, Ameur LB, De Maria M, Saunders A, Lobingier BT
Sci Adv. 2026 Mar 20;12(12):eadx8715. doi: 10.1126/sciadv.adx8715. Epub 2026 Mar 20. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
250759puDNA5_SSF_MOR_WT_APEX2Mammalian cell expression of the wildtype mu opioid receptor
250766pcDNA5_TO_FRT_myc_GLUT4_WT_APEX2Mammalian cell expression of GLUT4

Antibodies from Article