Integrative CRISPR Screening and RNA Analyses Discover an Essential Role for PUF60 Interactions with 3' Splice Sites in Cancer Progression.
Tankka AT, Zhang Y, Einstein JM, Zhou CJ, Pham VN, Naritomi JT, Nguyen GG, Mendez-Molina AN, Hu Z, Mizrahi O, Perelis M, Sarsam J, Tan FE, Kaufman DS, Yang J, Antal CE, Yeo GW
Cancer Res. 2025 Dec 18:10.1158/0008-5472.CAN-25-0453. doi: 10.1158/0008-5472.CAN-25-0453.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 250988 | RNA-Binding Protein Pooled CRISPR Knockout In Vivo Library | CRISPR knockout library targets 206 RBPs with 5 single-guide RNAs (sgRNAs) per target. It is constructed in the lenti-CRISPR V2 backbone, enabling doxycycline-inducible expression of Cas9. |