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Rapid UPF1 depletion illuminates the temporal dynamics of the NMD-regulated human transcriptome.

Boehm V, Wallmeroth D, Wulf PO, Popp O, Teixeira Alves LG, Reinecke L, Riedel M, Wyler E, Franitza M, Becker K, Polkovnychenko K, Del Giudice S, Benlasfer N, Mertins P, Landthaler M, Gehring NH
Mol Cell. 2025 Sep 18;85(18):3524-3546.e12. doi: 10.1016/j.molcel.2025.08.015. Epub 2025 Sep 10. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
251491px458-Cas9 UPF1 sgRNACas9 CRISPR gRNA construct; expresses human UPF1 gRNA

Antibodies from Article