Rapid directed evolution guided by protein language models and epistatic interactions.
Tran VQ, Nemeth M, Bartie LJ, Chandrasekaran SS, Fanton A, Moon HC, Hie BL, Konermann S, Hsu PD
Science. 2026 Feb 19:eaea1820. doi: 10.1126/science.aea1820.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 252076 | pVT0494 MULTI-assembly vector with HuABC2 Variable Heavy Domain | Vector for MULTI-assembly cloning for HuABC2 Variable Heavy Domain variants; replace HuABC2 insert with gene of interest via Gibson Assembly |