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Unraveling mitochondrial influence on mammalian pluripotency via enforced mitophagy.

Schmitz DA, Oura S, Li L, Ding Y, Dahiya R, Ballard E, Pinzon-Arteaga C, Sakurai M, Okamura D, Yu L, Ly P, Wu J
Cell. 2025 Aug 21;188(17):4773-4789.e22. doi: 10.1016/j.cell.2025.05.020. Epub 2025 Jun 10. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
252078rtTA-PuroR, Mito-EGFP-OMM-PINK1-PRKNA PiggyBac donor vector that allows for the Dox-inducible expression of mito-EGFP, OMM-PINK1, and PRKN for enforced mitophagy in mammalian cells.
252080rtTA-HygR-Mito-EGFP, OMM-PINK1-PuroR-PRKNA PiggyBac donor vector that allows for the Dox-inducible expression of mito-EGFP, OMM-PINK1, and PRKN for enforced mitophagy in mammalian cells.

Antibodies from Article