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An inducible model of human post-implantation development derived from primed and naive stem cells.

Oura S, Li L, Wu J
Cell Stem Cell. 2025 Oct 2;32(10):1509-1527.e9. doi: 10.1016/j.stem.2025.08.005. Epub 2025 Aug 29. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
252248ePB-Puro_TT-hGATA6-T2A-EGFP-CAAXA PiggyBac donor vector for Dox-inducible expression of GATA6 and membrane-localized EGFP.
252249ePB-Puro_TT-hCDX2-P2A-tdTomato-CAAXA PiggyBac donor vector for Dox-inducible expression of CDX2 and membrane-localized tdTomato.
252250ePB-Puro_TT-hGATA3-P2A-tdTomato-CAAXA PiggyBac donor vector for Dox-inducible expression of GATA3 and membrane-localized tdTomato.
252251ePB-Puro_TT-hYAP-5SA-P2A-tdTomato-CAAXA PiggyBac donor vector for Dox-inducible expression of YAP-5SA and membrane-localized tdTomato.

Antibodies from Article