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Inwardly rectifying potassium channels promote directional sensing during neutrophil chemotaxis.

Wang T, Kim DH, Ding C, Wang D, Zhang W, Silic M, Cheng X, Shao K, Ku T, Zheng C, Xie J, Xiao S, Jayant K, Yuan C, Chubykin AA, Staiger CJ, Zhang G, Deng Q
J Cell Biol. 2026 Jan 5;225(1):e202503037. doi: 10.1083/jcb.202503037. Epub 2025 Nov 19. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
254782Tol2-lyzC-ASAP3-2a-TagBFP-caaxASAP3 (ASAP-family genetically encoded voltage indicator) overexpression in zebrafish neutrophils with TagBFP membrane label
254783Tol2-LyzC-GtACR2-tdTomatotdTomato fused optogenetic opsin GtACR2 overexpression in zebrafish neutrophils.
254784Tol2-LyzC-BLINK2-2a-mcherry caaxOptogentic tool BLINK2 overexpression in zebrafish neutrophils with membrane label.
254786Tol2-LyzC-PHAKT-mCerulean3Membrane PIP3 level reporter of zebrafish neutrophils
254787Tol2-LyzC-mCherry-CAAXmCherry C-terminally tagged with the CaaX sequence. Neutrophil membrane control.
254788Tol2-LyzC-GFP-2a-PTXPertussis toxin (PTX) overexpression in GFP tagged zebrafish neutrophils

Antibodies from Article