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Nanobodies targeting EGFR provide insight into conformations stabilized by glioblastoma mutations.

Watson SM, Harvey EP, Pishesha N, Ploegh HL, Springer TA
J Biol Chem. 2025 Jul;301(7):110374. doi: 10.1016/j.jbc.2025.110374. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
253818EGFR-R84K-ET1Expression of full length EGFR with R84K mutation
253821EGFR-G574V-ET1Expression of full length EGFR with G574V mutation

Antibodies from Article